Spennymoor FC are to host a football match where heading the ball will be restricted in the first half and completely disallowed in the second half.
The game is a 'pilot' to see how the restrictions work.
It is being backed by brain charity Head for Change, who are organising the match along with the Solan Connor Fawcett Family Cancer Trust.
Research by Dr Willie Stewart and his University of Glasgow team have found what they described as the ‘missing link’ between repetitive heading and neurodegenerative disease.
Defenders, who head the ball the most, have a five-fold risk of developing dementia compared to the general public. Goalkeepers, who hardly ever head the ball, have no increased risk.